allodynia semaglutide treatment GLP-1 Drugs: New Reports of Dysesthesia and Semaglutide Ameliorates Diabetic Neuropathic Pain

These effects occurred at doses comparable to those used in humans for weight loss, not just extreme overdose scenarios

It was found that semaglutide, a long-acting GLP-1RA, could improve symptoms caused by sepsis, reduce body temperature, and decrease the bacterial load in multiple organs, along with the levels of inflammatory factors in plasma and lungs.423 These findings further confirmed the central role of the CNS in regulating the anti-inflammatory effects of GLP-1RAs, highlighting the potential application of GLP-1RAs in anti-inflammatory treatment

[1] [2] Additional important safety considerations include risk of pancreatitis, gallbladder disease, hypoglycemia (especially when used with insulin or sulfonylureas), and acute kidney injury associated with severe gastrointestinal adverse reactions

No clinic visit